Virtual Laboratory for Undergraduate Electrical Engineering Students
Explore Doppler radar techniques for non-invasive blood flow velocity measurement
Upon completion of this virtual laboratory, students will be able to:
Fundamental concepts underlying radar-based blood flow measurement
When a radar wave reflects off moving blood cells (erythrocytes), the frequency of the reflected wave shifts proportionally to the velocity of the blood. This phenomenon, first described by Christian Doppler in 1842, forms the basis of all Doppler flow measurement systems.
Where v = blood velocity, ft = transmit frequency, θ = Doppler angle, and c = speed of sound in tissue (~1540 m/s).
CW Doppler radar transmits a continuous sinusoidal wave and receives the reflected signal simultaneously. Two separate transducers (or one with duplexer) are typically used. CW systems can measure very high velocities but cannot determine depth.
PW Doppler transmits short bursts of ultrasound/radar energy and listens for echoes during the quiet intervals. By controlling the time delay before sampling, specific depths (sample volumes) can be interrogated.
Blood is a non-Newtonian fluid containing plasma and formed elements. Erythrocytes (red blood cells) act as the primary scatterers for radar/ultrasound waves due to their size (~7-8 μm) and concentration.
| Vessel | Velocity Range | Flow Type |
|---|---|---|
| Aorta | 20 - 100 cm/s | Pulsatile |
| Carotid Artery | 30 - 80 cm/s | Pulsatile |
| Femoral Artery | 10 - 50 cm/s | Pulsatile |
| Peripheral Veins | 5 - 20 cm/s | Phasic |
| Capillaries | 0.03 - 0.3 cm/s | Steady |
The cosine dependence on angle is critical. At 0° (directly in line with flow), sensitivity is maximum. At 90° (perpendicular), no Doppler shift is detected. Clinical practice recommends keeping θ ≤ 60°.
While medical ultrasound (1-15 MHz) is most common, microwave radar (1-10 GHz) offers contactless operation through clothing. Radar-based systems use phase detection and can measure sub-millimeter displacements.
At 2.4 GHz, detecting 1 cm/s blood flow requires measuring ~160 Hz Doppler shift — challenging but feasible with modern DSP.
The received Doppler signal undergoes several processing stages:
The Doppler spectrum shows velocity distribution:
Adjust parameters and observe real-time Doppler shift calculations and spectra
Step-by-step experimental procedure for the virtual laboratory
Launch the Doppler radar simulation. Verify that the transmit frequency is set to 5.0 MHz (typical for peripheral vascular studies). Set the speed of sound constant to c = 1540 m/s for soft tissue. Confirm that the Doppler angle display is calibrated to 0° when the beam is parallel to the vessel.
Set blood velocity to a constant 50 cm/s. Vary the Doppler angle θ from 0° to 80° in increments of 10°. Record the Doppler shift frequency (fd) at each angle. Plot fd versus cos(θ) and verify linearity. Calculate the percentage error in velocity estimation if the angle is misestimated by ±5° at θ = 30°, 45°, and 60°.
Fix the Doppler angle at 45°. Sweep blood velocity from 0 to 150 cm/s in 10 cm/s steps. Record fd for each velocity setting. Plot fd versus v and determine the slope. Compare the experimental slope with the theoretical value: (2·ft·cosθ)/c. Calculate the coefficient of determination (R²).
Set velocity to 100 cm/s and angle to 30°. Vary transmit frequency from 1 MHz to 10 MHz. Record fd at each frequency. Discuss the trade-off: higher frequencies provide larger Doppler shifts (easier detection) but suffer greater tissue attenuation (α ∝ f²). Calculate the penetration depth if attenuation coefficient is 0.5 dB/cm/MHz.
Switch to PW Doppler mode (simulated). Set PRF to 5 kHz. Increase velocity gradually until aliasing is observed in the spectral display. Record the velocity at which aliasing first occurs and compare with the theoretical Nyquist limit: vmax = (PRF · c) / (4 · ft · cosθ). Repeat for PRF values of 8 kHz and 15 kHz.
Observe the waveform display for different velocity profiles. Simulate arterial flow by setting a pulsatile pattern (systolic peak ~120 cm/s, diastolic ~40 cm/s). Compare with venous flow (steady ~15 cm/s). Identify features: systolic upstroke, deceleration phase, diastolic flow, and resistive index (RI = (vsyst - vdiast) / vsyst).
Add simulated noise to the received signal. Gradually increase noise power until the Doppler spectrum becomes indistinguishable. Record the SNR threshold. Discuss how SNR affects the minimum detectable velocity and the accuracy of spectral broadening measurements.
Simulate vessel wall motion at 0.5 cm/s (low velocity, high amplitude). Apply high-pass wall filters with cutoff frequencies of 50 Hz, 100 Hz, and 200 Hz. Observe how each filter affects the displayed spectrum. Determine the optimal cutoff that removes wall clutter while preserving true flow information.
Structure and content requirements for the laboratory report
| Component | Points | Criteria |
|---|---|---|
| Abstract & Introduction | 15 | Clarity, completeness, citations |
| Theory & Derivations | 15 | Correctness, rigor, diagrams |
| Methodology | 10 | Reproducibility, detail |
| Results & Graphs | 20 | Accuracy, presentation, error analysis |
| Discussion | 20 | Depth, critical thinking, clinical relevance |
| Conclusion & References | 10 | Synthesis, formatting |
| Grammar & Presentation | 10 | Professional writing, adherence to format |
Test your understanding of radar principles for blood flow measurement